Phytochemical Screening, GC-MS Study, FTIR analysis and antimicrobial activities of ethanol extracts of Tetrapleura tetraptera fruit
1 Department of Chemistry, Hallmark University, Ijebu-Itele, Nigeria.
2 Department of Pure and Applied Biology, Ladoke Akintola University of Technology, Ogbomosho, P.M.B. 4000, Nigeria.
3 Department of Science Laboratory Technology, Federal College of Fishery and Marine Technology, Victoria Ireland Land Lagos, Nigeria.
4 Department of Science Laboratory Technology, Westland Polytechnic, Ilobu, Nigeria.
5 Department of Medical Laboratory Technology, Crestfield College of Health Sciences and Management Technology, Erin Osun, Nigeria.
Research Article
International Journal of Frontiers in Science and Technology Research, 2024, 07(02), 109-118.
Article DOI: 10.53294/ijfstr.2024.7.2.0060
Publication history:
Received on 13 November 2024; revised on 22 December 2024; accepted on 24 December 2024
Abstract:
Introduction: Antimicrobial and phytochemical properties have been associated with the therapeutic effects of plants. This study aimed to qualitatively assess the Tetrapleura tetraptera fruit ethanol extract for phytoconstituents.
Method: The extract was subjected to GC-MS and FTIR analysis to identify bioactive components and functional groups. The Mycelial Inhibition Method was employed to evaluate the extract's antifungal properties against selected microorganisms. In the phytochemical screening, the ethanol extract exhibited the presence of all examined phytochemicals.
Results: GC-MS analysis revealed 15 compounds from 6 recognized classes, with Ethyl Oleate (48.21%), 9-Octadecenoic acid, (E)- (19.18%), 9-Oxabicyclo [6.1.0] nonane, cis- (8.86%), Hexadecanoic acid, ethyl ester (6.24%), and 9,12-Octadecadienoic acid, ethyl ester (4.46%) being the principal chemical components. Results from FTIR analysis indicated significant chemical functional groups in the ethanol extract. Moreover, the extract demonstrated enhanced antimicrobial activity compared to the control, suggesting its potential therapeutic applications. Conclusion: These findings imply that Tetrapleura tetraptera could serve as a source of bioactive substances.
Keywords:
Tetrapleural tetraptera; FTIR; Phytochemical screening; antimicrobial activity; GC-MS
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