Preliminary Hazard Analysis (PHA): Great approach to risk analysis in pharmaceutical industry

Soniya Kundnani *, Dhara Patel and Dhananjay Meshram

Department of Pharmaceutical Quality Assurance, Pioneer Pharmacy College, Nr. Ajwa Crossing, Sayajipura, Vadodara, Gujarat, India.
 
Review
International Journal of Frontiers in Science and Technology Research, 2022, 03(02), 005–018.
Article DOI: 10.53294/ijfstr.2022.3.2.0055
Publication history: 
Received on 03 October 2022; revised on 15 November 2022; accepted on 17 November 2022
 
Abstract: 
Preliminary Hazard Analysis (PHA) is a semi-quantitative evaluation executed to recognize, early within side the layout and definition level of a system, all potential hazards and hazardous events that can cause an accident, classify identified hazardous events according to their severity and identify the required hazard controls and their respective follow-up actions.  It is a great tool for beginning to recognize the hazards of a system. In some cases, a PHA is all that is needed to analyse a simple system. It is also the first step in the hazard analysis of more complicated systems. This review illustrates PHA's use for analysing a maintenance process/procedure and discusses the injuries that can occur with poor design and recommend solutions.
 
Keywords: 
Preliminary Hazard Analysis; Accident; Recognise; Follow-up actions
 
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