Exploring the pharmacological potentials of green synthesized nanoparticles of Clerodendrum infortunatum Linn.
1 M. Pharm Student, Department of Pharmacology, Kerala University of Health Sciences, College of Pharmaceutical Sciences, Government Medical College, Kannur, Kerala, India.
2 Assistant Professor, Department of Pharmacology, Kerala University of Health Sciences, College of Pharmaceutical Sciences, Government Medical College, Kannur, Kerala, India.
Review
International Journal of Frontiers in Science and Technology Research, 2024, 07(01), 035–047.
Article DOI: 10.53294/ijfstr.2024.7.1.0047
Publication history:
Received on 13 June 2024; revised on 31 July 2024; accepted on 03 August 2024
Abstract:
Clerodendrum infortunatum Linn., a widely cultivated shrub known for its extensive medicinal properties, has emerged as a valuable resource for the green synthesis of metallic nanoparticles. This review discusses the synthesis of silver, zinc oxide, and gold nanoparticles using extracts from various parts of the plant. The nanoparticles were comprehensively characterized, revealing unique structural and morphological features. Evaluations of their pharmacological activities demonstrated remarkable antibacterial efficacy for silver nanoparticles, potent anthelminthic activity for both silver and gold nanoparticles, and significant anticancer potential for gold nanoparticles against leukemic cells. Additionally, zinc oxide nanoparticles exhibited strong antioxidant and antifungal properties. These findings highlight the versatility and therapeutic potential of nanoparticles synthesized from Clerodendrum infortunatum, emphasizing its importance in green nanotechnology and drug development.
Keywords:
Clerodendrum infortunatum; Green synthesis approach; Silver nanoparticles; Zinc oxide nanoparticles; Gold nanoparticles
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