Utility of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in non-alcoholic liver cirrhosis
Department of General Medicine BGS Global Institute Of Medical Science, Bangalore, India.
Research Article
International Journal of Frontiers in Medicine and Surgery Research, 2023, 03(01), 044–048.
Article DOI: 10.53294/ijfmsr.2023.3.1.0061
Publication history:
Received on 20 April 2023; revised on 28 May 2023; accepted on 30 May 2023
Abstract:
The purpose of this research is to determine whether or not there is a correlation between a high neutrophil-to-lymphocyte ratio (NLR) and a high platelet-to-lymphocyte ratio (PLR) and nonalcoholic fatty liver disease (NAFLD).
Methods: This was a retrospective study in the medicine department of a tertiary care facility. The demographic and clinical data was retrieved in a methodical fashion from the case records. Along with this, the data regarding the biopsy and other laboratory parameters was recorded to. This data was compared with non-NAFLD patients.
Results: The non-NAFLD participants were separated from the NAFLD subjects and placed in one of the two groups. According to the findings of our investigation, a low PLR score was connected with a higher risk of NAFLD (P 0.001), whereas a high NLR score was not significantly linked to NAFLD (P > 0.05). While there was shown to be a positive correlation between NLR and NAFLD, a negative association between PLR and NAFLD was discovered to exist.
Conclusion: The findings of this study indicated that a strong association exists between NLR and PLR and NAFLD. we According to the findings, a lower PLR and NLR could be a risk factor for morbidity in NAFLD patients.
Keywords:
Nonalcoholic fatty liver disease; Neutrophil-to-lymphocyte ratio; Platelet-to-lymphocyte ratio
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