Utility of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in non-alcoholic liver cirrhosis

MS Ravishankar Shashank S Gowda, Harshith CS, Balachandra G and Sahana G *

Department of General Medicine BGS Global Institute Of Medical Science, Bangalore, India.
 
Research Article
International Journal of Frontiers in Medicine and Surgery Research, 2023, 03(01), 044–048.
Article DOI: 10.53294/ijfmsr.2023.3.1.0061
Publication history: 
Received on 20 April 2023; revised on 28 May 2023; accepted on 30 May 2023
 
Abstract: 
The purpose of this research is to determine whether or not there is a correlation between a high neutrophil-to-lymphocyte ratio (NLR) and a high platelet-to-lymphocyte ratio (PLR) and nonalcoholic fatty liver disease (NAFLD).
Methods: This was a retrospective study in the medicine department of a tertiary care facility. The demographic and clinical data was retrieved in a methodical fashion from the case records. Along with this, the data regarding the biopsy and other laboratory parameters was recorded to. This data was compared with non-NAFLD patients.
Results: The non-NAFLD participants were separated from the NAFLD subjects and placed in one of the two groups. According to the findings of our investigation, a low PLR score was connected with a higher risk of NAFLD (P 0.001), whereas a high NLR score was not significantly linked to NAFLD (P > 0.05). While there was shown to be a positive correlation between NLR and NAFLD, a negative association between PLR and NAFLD was discovered to exist.
Conclusion: The findings of this study indicated that a strong association exists between NLR and PLR and NAFLD. we According to the findings, a lower PLR and NLR could be a risk factor for morbidity in NAFLD patients.
 
Keywords: 
Nonalcoholic fatty liver disease; Neutrophil-to-lymphocyte ratio; Platelet-to-lymphocyte ratio
 
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