The correlation between duration of illness and hemoglobin A1c levels with quality of life in children with type 1 diabetes mellitus

Garindra Wicaksono 1, 2, Ahmad Suryawan 1, 2, *, Anang Endaryanto 1, 2, Nur Rochmah 1, 2 and Muhammad Faizi 1, 2

1 Department of Pediatric, Faculty of Medicine Universitas Airlangga 60132, Surabaya, East Java, Indonesia.
2 Dr. Soetomo General Hospital 60286, Surabaya, East Java, Indonesia.
 
International Journal of Frontiers in Medicine and Surgery Research, 2021, 01(01), 019–024.
Article DOI: 10.53294/ijfmsr.2021.1.1.0062
Publication history: 
Received on 25 March 2021; revised on 27 April 2021; accepted on 30 April 2021
 
Abstract: 
Children with type 1 diabetes mellitus (T1DM) are in a chronic condition that requires daily care throughout life and interferes the quality of life. This research was an analytical observational study with a cross-sectional design at the Pediatric Endocrinology Outpatient Clinic in Dr. Soetomo General Hospital, Surabaya. The sample size of this study was 29 subjects. Data were accumulated through interviews, questionnaires, and medical records. To determine whether there is a relationship among the duration of illness, HbA1c levels, and the quality of life in children with T1DM, a correlation test with Pearson will be conducted. The Multiple Linear Regression test was carried out to determine how big the influence of the relationship. The results showed that from a total sample of 34 subjects, the average duration of illness was 21.24 (±14.82) months, the highest HbA1c level was 9 (6-13) %. The analysis results with the independent sample T-test were obtained with a value of p=0.877 (p <0.05), means that there was no notable difference between children and parents reports. The relationship among duration of illness, HbA1c, and quality of life were analyzed by Pearson Correlation test and Multiple Linear Regression test. The correlation results for length of illness and HbA1c sequentially r= 0.743, r= -0.857 with R2 value: 78.4% and p=0.001(p<0.05). From this study, it was also found that there was a positive relation between duration of illness and quality of life along with a negative correlation between HbA1c and quality of life.
 
Keywords: 
Duration of illness; HbA1c; Quality of Life; Type 1 Diabetes Mellitus
 
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