Assessment of creatinine and blood urea in kidney failure patient within Kerkuk city, Iraq
1 Department of Chemistry, Faculty of Education for Pure Science, University of Kerkuk, Iraq.
2 Department of Basic Science, Faculty of Dentistry, University of Al-Kitab; Kerkuk, Iraq.
Research Article
International Journal of Frontiers in Life Science Research, 2023, 05(02), 008–013.
Article DOI: 10.53294/ijflsr.2023.5.2.0084
Publication history:
Received on 21 September 2023; revised on 20 November 2023; accepted on 23 November 2023
Abstract:
The assessment of creatinine, a waste product produced by muscle metabolism that is filtered out of the body by the kidneys and the levels of blood urea are important tools for monitoring kidney's function. A total of 191 patients (105 male and 86 female) encountered in this study, with kidney failure compared with 21 control healthy individuals (11 male and 10 female). A significant increase (p≤0.0012) in creatinine was detected in kidney failure patients (9.3±3.2) in comparison with control (0.62±0.1) as well as between the genders. In female the creatinine level was significantly higher (p≤0.05) than that of male. The general levels of urea have also elevated in kidney failure disease (KFD) from (112±42) in comparison with control (25±10) but with a slight significant difference (p≤0.05) between the genders. The percentages of Hb% showed a significant decrease (p≤0.007) in kidney failure patients in comparison with control of all cases. Similarly, the packed cell volume (PCV) had significantly dropped down (p≤0.01) in total patients as well as in between genders in comparison with their counter control. Increased urea 4-5 folds in kidney patients confirms, to certain extend, the occurrence of dysfunction of kidneys and failure to re-absorb the nitrogen components leading to elevation of its amount in patients. Regular monitoring of creatinine and blood urea levels, along with other factors deems essential for improving patient health and quality of life.
Keywords:
Biochemistry; Blood urea; Creatinine; Kerkuk; Kidney failure.
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