Microbiological profile and antibiotic resistance of urinary tract infections in Maternity and Children Hospital, Hafr Al Batin, Saudi Arabia within 2022
1 Department of Clinical Laboratory Sciences, College of Applied Medical Science, University of Hafr Al Batin, P.O. Box 1803, Hafar Al Batin 31991, Saudi Arabia.
2 Department of Microbiology, College of Pharmacy, University of Hafr Al Batin, P.O. Box 1803, Hafr Al Batin 31991, Saudi Arabia.
3 Department of Oral Medicine and Diagnosis Science, Faculty of Dentistry, October University for Modern Sciences and Arts (MSA), Giza, Egypt.
4 Department of Biology, College of Sciences, University of Hafr Al-Batin, P.O. Box 1803, Hafr Al-Batin 31991, Saudi Arabia.
5 Department of Clinical Pharmacy, Faculty of Pharmacy, October University for Modern Sciences and Arts ((MSA), Giza, Egypt.
Research Article
International Journal of Frontiers in Biology and Pharmacy Research, 2023, 04(02), 001–009.
Article DOI: 10.53294/ijfbpr.2023.4.2.0019
Publication history:
Received on 13 October 2023; revised on 26 October 2023; accepted on 29 November 2023
Abstract:
Objective: This study aimed to characterize the antibiotic sensitivity, microbial resistance, and prevalence of the bacteria responsible for urinary tract infections (UTIs) at Maternity and Children Hospital (MCH), Hafr Al Batin, Saudi Arabia.
Methods: Analysis was done on 1273 culture samples that were processed in the microbiology lab between January and December of 2022.
Results: In all, 1273 urine culture (UC) samples were gathered. Gram-negative bacteria accounted for 46.9% of the 1273 positive UC, followed by Gram-positive bacteria with 28.8%, fungal pathogens with 13.1%, and Gram-negative non-fermenting bacteria with 11.2%. The most common uropathogenic organism (76.8%) was Pseudomonas aeruginosa, which was followed by Escherichia coli (55.6%), Staphylococcus epidermidis (22.9%), and Klebsiella pneumonia (24.3%). Candida albicans (69.5%) was determined to be the most frequent agent in terms of fungus, followed by C. glabrata (19.2%). The study revealed that the bacterial isolates exhibited effective resistance to antimicrobial drugs such as Amikacin, Cefepime, Ciprofloxacin, Gentamicin, imipenem, Levofloxacin, and Piperacillin/Tazobactam when administered against Gram-negative bacteria. Furthermore, the most effective antibiotics against Gram‑positive was Erythromycin but were sensitive to Vancomycin.
Conclusions: One of the most typical infections that affect women is bacterial urinary tract infection. Using antibiotics for a very long time, and their misuse will result in the widespread growth of resistant bacteria.
Keywords:
Urinary tract infections; Gram-negative Bacteria; Gram-positive Bacteria antibiotic susceptibilities; Fungi; Saudi Arabia
Full text article in PDF:
Copyright information:
Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0